The overall theme is making more than the 23 nonland cards in your deck matter. To that end, I've included conspiracies and draft interaction cards from Conspiracy, lesson/learn spells from Strixhaven, spell lands from Zendikar Rising, a few companions, and abundant land-based mana fixing.
There are 10 main archetypes, one for each color pair.
White-Blue: Flicker
Blue-Black: Cycling
Black-Red: Madness
Red-Green: Go-big agro
Green-White: +1/+1 counters
White-Black: Artifact tokens
Blue-Red: Spells/Pyromancers
Black-Green: Recursive agro
Red-White: Go-wide aggro
Green-Blue: Kicker and Ramp
ERRATA: Arcane Savant's ability only triggers if it was cast. Backup Plan paired with Sovereign's realm does not allow you to draw an extra hand of 7 cards. Companions are played as-written and can be cast directly from the command zone.
Changes to reinforce archetypes, incorporate cards from recent sets, and remove Universes Beyond from the cube.