The manlands always felt out of place in the cube : coming to the battlefield tapped was too much of a loss of tempo, and with 3 painlands and 4 fetches, there is already enough fixing for 2 players.
On the other hand, the desert cycle from Hour of Devastation seems like it was meant to be in this cube. Each of the 3 deserts provides a nice effect in line with its color game plan and costs life to be used. They make for a nice redundancy with the Odyssey lands as "Spell lands". Since the mana curves tend to be pretty low, it's always nice to have a side effect on some of the lands.
The three 7-mana creatures were pretty underwhelming, and Mirroshell Crab was the only one seeing real play, so they were all replaced with cheaper creatures. At the same time, I decided to add a reconfigure creature to each color.
Mirrorshell Crab -> Hypnotic Sprite
Archfiend of Sorrows -> Leech Gauntlet
Chancellor of the Forge -> Lizard Blades
I felt that only red should be able to consistantly create token, so I replaced the blue and black token generators. Moreover, Sedgemoor Witch was way too powerful.
Nadir Kraken -> Acquisition Octopus
Sedgemoor Witch -> Callous Bloodmage
Other changes :
Knight of the Ebon Legion -> Foulmire Knight because it was too powerful compared to the other one-drops
Vampire Nighthawk -> Fell Stinger because the card wasn't really fun to play or versatile
Nekrataal -> Corpse Augur because black already had too much removal and Nekrataal was the least interesting
Filth -> Graveborn Muse because Filth is the worst of all incarnations
Disfigure -> Lash of Malice because the card is more versatile
Flame Javelin -> Electric Revelation because each other color now has at least one draw engine, and Flame Javelin wasn't good enough.