This cube is built around the 10 two-color pairs, with each color pair having two supported themes.

Azorius
Primary: Blink
Secondary: Flying

Dimir
Primary: Combat Damage
Secondary: Graveyard

Rakdos
Primary: Sacrifice
Secondary: Aggro

Gruul
Primary: Power Matters
Secondary: Stompy

Selesnya
Primary: Tokens
Secondary: +1/+1 Counters

Orzhov
Primary: Lifegain
Secondary: Aristocrats

Izzet
Primary: Spellslinger
Secondary: Draw Cards

Golgari
Primary: Graveyard
Secondary: Sacrifice

Boros
Primary: Equipment
Secondary: Tokens

Simic
Primary: +1/+1 Counters
Secondary: Ramp/Tempo